Direct oral anticoagulants are associated with limited damage of endothelial cells of the blood-brain barrier mediated by the thrombin/PAR-1 pathway

Clémentine Puech (1, 2) , Xavier Delavenne (1, 2, 3) , Zhiguo He (4) , Valérie Forest (1) , Patrick Mismetti (1, 2, 5) , Nathalie Perek (1, 2)

1 SAINBIOSE - Santé Ingénierie Biologie Saint-Etienne
2 Université de Lyon, Saint-Etienne, F-42023, France
3 Laboratoire de Pharmacologie Toxicologie [CHU Saint-Etienne]
4 BIIO - Biologie, Ingénierie et Imagerie pour l'Ophtalmologie
5 Unité de Recherche Clinique Innovation et Pharmacologie, CHU de Saint-Etienne, F-42055 Saint Etienne, France

Domaines: Sciences du Vivant [q-bio]

Clémentine Puech, Xavier Delavenne, Zhiguo He, Valérie Forest, Patrick Mismetti, et al.. Direct oral anticoagulants are associated with limited damage of endothelial cells of the blood-brain barrier mediated by the thrombin/PAR-1 pathway. Brain Research, 2019, 1719, pp.57-63. ⟨10.1016/j.brainres.2019.05.024⟩. ⟨hal-02309490⟩